Does the foot-and-mouth vaccine still work when it’s frozen? Does foot-and-mouth Disease Vaccine Affect Pregnant Ewes? Foot-and-mouth disease (FMD) , also known as “APHTHA”or “Pihuang”, is an acute, Febrile, highly contagious disease of cloven-hoofed animals caused by FMD virus. 

Vaccination can play a preventive role related to the foot-and-mouth disease vaccine pregnant ewes can play?

Does the foot-and-mouth vaccine still work when it’s frozen? 

No. 

Foot-and-mouth disease vaccine can be refrigerated but not frozen. Because the foot-and-mouth disease (FMD) vaccine is stored at 2 ~ 8 °C above zero, either too low or too high temperature has a bad effect on the storage of FMD vaccine. 

The foot-and-mouth Disease Vaccine Virus is inactivated, has lost its destructiveness and infectivity, and has lost its ability to reproduce and destroy. The virus is actually a living protein, and when the protein is frozen, it crystallizes, and the crystal pierces the whole protein, and the whole viral protein vaccine is completely dead, and the vaccine is ineffective. 

Does foot-and-mouth Disease Vaccine Affect Pregnant Ewes? Normally pregnant ewes can not be vaccinated against foot-and-mouth disease because of the risk of miscarriage. 

To avoid the vaccine on its impact,  Fortunately before the Ewe breeding 45 days or post-weaning injection of foot-and-mouth vaccine, can play a certain control effect.