Description

GRDR-ATSB injection is a broad-spectrum semi-synthetibactericidal macrolide antibiotic synthesized from tylosin. It has anantibacterial spectrum that is predominantly effective against Mycoplasma, Pasteurella and Haemophilus spp and vanous Grampositive organisms such as Staphylococcus spp.

Composition  Contains per ml

Azithromycin  4000000U

Tilmicosin base 100mg

Bromhexine  2mg

Solvents ad  1ml

Indications

ATSB injection is indicated for the treatment of respiratory infectionsin cattle and sheep associated with Mannheimia haemolyticaPasteurella spp, and for the treatment of ovine mastitis associatedwith Staphylococcus aureus and Mycoplasma spp. Additionalindications include the treatment of interdigital necrobacillosis incattle(bovine pododermatitis, foul in the foot) and ovine footrot.

Contra indications

Hypersensitivity or resistance to tilmicosin and azithromycin.Do not use in lactating animals. During pregnancy, use only after arisk/benefit assessment by a veterinarian. Do not use in heifers within 60 days of calvingDo not use together with adrenalin or p-adrenergic antagonists suchs propranolo

Side effects

Occasionally, a soft diffuse swelling may occur at the injection sitewhich subsides without further treatment. The acute manifestations ofmultiple injections of large subcutaneous doses(200 mg/kg)in cattleincluded moderate electrocardiographic changes accompanied bymild focal myocardial necrosis, marked injectionsite oedema , and death . Single subcutaneous injections of 50 mg / kgin sheep produced increased respiration rate , and at higher levels( 200 mg / kg ) ataxia , lethargy and drooping of the headosage

For subcutaneous injection

Cattle  pneumonia 3 ml per 30 kg body weight ( 30 mg / kg) .

Cattle interdigital necrobacillosis 1.5 m per 30 kg body weigh 5 mg / kg )

Sheep  pneumonia and mastitis : 3 ml per 30 kg body weight( 30 mg / kg ) .

Sheep footrot : 1.5 ml per 30 kg body weight ( 15 mg / kg )

Note :

Exercise extreme caution and take appropriate measures toavoid accidental self-injection , since injection of this drug in humanscan be fatal ! ATSB injection should be administered only by aveterinary surgeon . Accurate weighing of animals is important toavoid over dosage . The diagnosis should be reconfirmed if noimprovement is noted within 48 h Administer once only

Withdrawal time

For meat Cattle : 60 daysSheep : 42 daysFor milkSheep : 15 days

Warning

Keep out of reach of children

Packing

Vial / 100 ml