Levamisole HCl CAS 16595-80-5
PRODUCT INFORMATION
| Substance Name | Levamisole HCL |
| Synonyms |
* Levasole, Tetramisole hydrochloride, Levomysol hydrochloride,
* 14769-73-4, * 24593-45-1, * 39170-95-1, * 74191-78-9,
* (-)-2,3,5,6-Tetrahydro-6-phenylimidazo(2,1-b)thiazole monohydrochloride,
* Ascaridil, * C07906, * Citarin L, * Decaris, * Dekaris, * DRG-0245,
* EINECS 240-654-6, * Ergamisol, * Ergamisol (TN),
* Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)- (8CI),
* Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (S)-,
* Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, L-(-)-,
* KW 2LE-T, * KW-2-LE-T,
* L-(-)-2,3,5,6-Tetrahydro-6-phenyl-imidazo(2,1-b)thiazole hydrochloride,
* Levacide, * Levadin, * Levamisole hydrochloride [USAN 1993],
* Levamisole hydrochloride [USAN], * Meglum, * Nemicide, * Nilverm forte,
* Niratic hydrochloride, * Niratic-puron hydrochloride, * NSC-177023,
* Stimamizol hydrochloride, * Tramisol, * Tramisole, * Worm-chek,
* R 12,564, * R 12564, * R-12,564, * Ripercol-L, * Solaskil, * Spartakon, |
| Chemical Name | (-) - (S) - 2, 3, 5, 6 – tetrahydro – 6 – phenylimidazo [2,1-b] thiazole monohydrochloride |
| Molecular Formula | C11H12N2S.HCl |
| Molecular Weight | 204.29+36.46=240.75 |
| CAS No. | 16595-80-5 |
| Chemical Structure | |
| Specification | EP/USP/CP |
|
Pharmacodynamic Properties |
Levamisole refers to Levo tetramisole, it is the Levo Isomer of tetramisole. It can selectively inhibit succinate dehydrogenase in parasite’s muscle so as to stop the reduction of succinic acid from fumaric acid. Therefore the parasite’s muscle metabolism lacks of oxygen and leads to decreasing of energy. L-isomer is active against helminthes with 1-2 times higher active efficiency and lower toxic and side effects than tetramisole. It is a broad spectrum anthelmintic with a very good activity against roundworms, hookworms, whipworms, and strongyloises stercoralis. It is an immunomodulator and has effect on rheumatic disorders. Levamisole is also a good alternative in cases of benzimidazole resistance. |
| Storage | Keep container tightly closed in a cool, well-ventilated area. |
| MSDS | Provide as per request after the order or contract is signed. |
Appearance:
White or Almost Crystalline Powder
Application:
It can selectively inhibit succinate dehydrogenase in parasite’s muscle so as to stop the reduction of succinic acid from fumaric acid. Therefore the parasite’s muscle metabolism lacks of oxygen and leads to decreasing of energy. Levamisole is also a good alternative in cases of benzimidazole resistance
Levamisole Hydrochloride Powder is an anthelmintic agent commonly used in large livestock such as cattle, pigs and sheep. Levamisole HCl is used in humans for diseases related to imbalances in the regulation of immune responses or deficiencies of the immune system, including autoimmune diseases, chronic and recurrent diseases, chronic infections and cancer. It has beneficial effects on host defense mechanisms and restores depressed immune responses in animals and humans. Another interesting use of levamisole in humans is as a treatment for common warts .
Caution:
Levamisole is not generally used in horses.
Withdraw Period:
Meat: 7 days.
Milk: 2 days.
Package:
25kg/drum
PICTURES
GMP CERTIFICATE
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