tags : bacitracin  zinc

Bacillus peptide was discovered by Johnson of Columbia University in 1943 in Bacillus sabtilis isolated from trauma of patients. Since its first discovery, it has been widely used in livestock and poultry breeding for its advantages of high efficiency, non-toxic side effects, no residues, no drug resistance and cross-resistance. In the subsequent studies, many excellent properties of bacitracin have been found, which has been widely used in veterinary medicine, animal feed additives and human clinic.

Action mechanism of bacitracin zinc

1. Inhibiting the proliferation of pathogenic microorganisms and promoting the growth of beneficial microorganisms

Zinc bacitracin has a strong antimicrobial effect on Gram-positive bacteria, and has obvious inhibitory effect on some gram-negative bacteria, actinomycetes and spirochetes, especially on Clostridium, Staphylococcus, Streptococcus, Corynebacterium, Neisseria and Salmonella.

2. Thinning the intestinal wall. Enhance permeability

Zinc bacitracin can reduce the production of ammonia and toxic amines in animal intestine and maintain the normal level of alkaline phosphatase in digestive tract by thinning the intestinal wall of livestock and poultry, enhancing the permeability of intestinal wall, and feeding zinc bacitracin, ultimately improving the metabolic environment to promote digestive absorption of nutrients.

3. Other roles

Bacillus peptide (zinc) indirectly affects the metabolic process and speed by affecting some beneficial intestinal microorganisms, enzymes, hormones and other active substances. Zinc ions are the components or activators of some microorganisms, enzymes and hormones, which affect the formation of blood cells and the metabolism of nucleic acids, proteins and carbohydrates. Bacillus peptide (zinc) can improve the basal metabolic rate, thyroid iodine utilization, cardiac blood output and liver blood volume in varying degrees.

Application effect

1. pigs. 

Adding bacilli peptide zinc to pig diets has obvious effect on increasing feed reward and promoting pig * * growth.

2. Chicken. 

With the increase of the dosage of bacitracin zinc in the compound preparation, the decrease of egg laying rate became smaller, and the quality of eggshell (eggshell strength, eggshell thickness) was significantly improved.

(this article《Application of Bacillus Peptide Zinc in Animal Production in 2019》is made up of veterinary drugs in the world. If you need to reprint, please specify the source. )